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LAUREN HULL
By LAUREN HULL

Cattle Drive Casserole

8 steps
Prep:20minCook:30min
Cattle Drive Casserole is a robust and flavorful layered dish that blends the bold spirit of the Old West with a touch of Tex-Mex flair
Updated at: Sat, 18 Jul 2026 22:06:38 GMT

Nutrition balance score

Unbalanced
Glycemic Index
56
Moderate
Glycemic Load
25
High

Nutrition per serving

Calories753.4 kcal (38%)
Total Fat47.4 g (68%)
Carbs45.5 g (18%)
Sugars12 g (13%)
Protein34.7 g (69%)
Sodium1438.3 mg (72%)
Fiber2.6 g (9%)
% Daily Values based on a 2,000 calorie diet

Instructions

Step 1
Preheat the oven to 350℉.
OvenOvenPreheat
Step 2
Heat a skillet over medium-high heat. Add the ground beef and break it apart with a spoon. Cook until no longer pink, stirring occasionally. Drain off any excess fat. (While the meat cooks, you can prepare the biscuit dough.)
lean ground beeflean ground beef1.5 pounds
Step 3
Prepare the Biscuit Dough: In a mixing bowl, combine the biscuit mix and water. Stir until well mixed, ideally using your hands for thorough blending. Spray a casserole dish with cooking spray and press the dough into the dish, spreading it out to the edges. Bake in the preheated oven for 5-8 minutes, or until the dough is set and lightly golden. Set aside, but keep the oven on.
Biscuit MixBiscuit Mix2 ½ cups
waterwater1 cup
Step 4
Add chopped onions and red bell pepper to the cooked ground beef. Stir and cook for about 4 minutes. Add taco seasoning and mix well. Remove from heat.
yellow onionyellow onion1
red bell pepperred bell pepper1
taco seasoning mixtaco seasoning mix1 ounce
Step 5
Spread the cooked ground beef mixture evenly on top of the baked biscuit layer.
Step 6
In a medium bowl, combine sour cream, mayonnaise, drained green chiles, ¾ cup shredded cheese, and garlic powder. Mix until smooth. Carefully spread this mixture over the ground beef layer.
BowlBowl
sour creamsour cream½ cup
mayonnaisemayonnaise½ cup
Green ChilesGreen Chiles4 ounces
Cheddar CheeseCheddar Cheese1 ½ cups
garlic powdergarlic powder1 teaspoon
Step 7
Add small spoonfuls of salsa over the sour cream layer (no need to spread it out). Sprinkle the remaining shredded cheese evenly on top.
Cheddar CheeseCheddar Cheese1 ½ cups
SalsaSalsa½ cup
Step 8
Place the casserole back in the oven, uncovered, and bake for 30 minutes or until hot and bubbly.
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