By Elliot Kaiser
Air-Fryer Spicy Fried Chicken Sandwich
Crispy, spicy air-fried chicken breast quarters coated in toasted panko and served on buns with hot mayo sauce, lettuce, and pickles or pickled jalapeños.
Updated at: Mon, 20 Jul 2026 02:47:06 GMT
Nutrition balance score
Good
Glycemic Index
69
Moderate
Glycemic Load
27
High
Nutrition per serving
Calories572.9 kcal (29%)
Total Fat31.3 g (45%)
Carbs37.4 g (14%)
Sugars1 g (1%)
Protein31.9 g (64%)
Sodium1005.1 mg (50%)
Fiber2 g (7%)
% Daily Values based on a 2,000 calorie diet
Ingredients
4 servings
2 x 8 ouncechicken breasts
4buns
iceberg lettuce
shredded
salt
pepper
1 cuppanko bread crumbs
2 tablespoonsextra-virgin olive oil
1egg
large
1 tablespoonflour
2 tablespoonshot sauce
½ teaspoongarlic powder
¼ teaspoonkosher salt
⅛ teaspoonblack pepper
¼ cupmayonnaise
1 tablespoonhot sauce
Pickles
or pickled jalapeños, for serving, optional
Instructions
Step 1
Preheat air-fryer to 400°F.
Step 2
Pound chicken breasts under plastic; cut off any fat and cut each breast into 4 equal parts. Pat dry and sprinkle with salt and pepper from about 6 to 8 inches above the chicken to evenly coat.
Step 3
Mix mayonnaise and hot sauce for the sauce; set aside.
Step 4
Add panko and olive oil to a bowl; mix to coat. Microwave for 1 to 3 minutes, stirring halfway through, to lightly toast. Spread into a wide dish to cool (for dredging).
Step 5
In another bowl, whisk egg, flour, hot sauce, garlic powder, kosher salt, and black pepper to combine.
Step 6
Set out a sheet pan or plate. Using one dry hand and one wet hand, dredge chicken pieces in egg/flour mixture; let excess drip off. Dredge in panko, pressing crumbs firmly onto the chicken. Place on sheet pan.
Step 7
Spray air-fryer with oil (Pam or other). Add chicken pieces and cook 12 to 16 minutes, starting with the lower time; flip halfway through. Chicken should be about 160°F. Remove and set aside.
Step 8
Toast buns (two halves at a time) in air-fryer for 1 minute.
Step 9
Assemble sandwiches: spread hot mayonnaise sauce on buns, add chicken, shredded lettuce, and pickles or pickled jalapeños.
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