Garlic Butter Chicken with Cheesy Penne Alfredo

Name: Garlic Butter Chicken with Cheesy Penne Alfredo
Prep time: 10 min
Cook time: 20 min
Total time: 30 min
Cuisine: European, Italian, Mediterranean
Ingredients: 1.5 lb boneless, skinless chicken breasts or thighs, cut into bite-size pieces; 2 tbsp butter; 1 tbsp olive oil; 1 tsp garlic powder; 1 tsp Italian seasoning; 0.5 tsp paprika; 1 tsp salt; 0.5 tsp black pepper; 12 oz penne pasta; 3 tbsp butter; 3 cloves garlic, minced; 1.5 cups heavy cream (or half-and-half); 1 cup chicken broth; 1 cup shredded mozzarella cheese; 1 cup grated Parmesan cheese; Fresh parsley, chopped (optional); Extra Parmesan cheese (optional)

8 steps

Prep:10minCook:20min

Creamy and cheesy penne Alfredo paired with tender garlic butter chicken, perfect for a satisfying weeknight meal or serving to guests.

Updated at: Mon, 16 Feb 2026 22:43:45 GMT

Nutrition balance score

Unbalanced

Glycemic Index

Low

Glycemic Load

High

Nutrition per serving

Calories780.4 kcal (39%)

Total Fat45.4 g (65%)

Carbs46.3 g (18%)

Sugars3.5 g (4%)

Protein45.3 g (91%)

Sodium895.9 mg (45%)

Fiber2 g (7%)

% Daily Values based on a 2,000 calorie diet

Ingredients

6 servings

1.5 lbboneless skinless chicken breasts

or thighs, cut into bite-size pieces

2 Tbspbutter

1 Tbspolive oil

1 tspgarlic powder

1 tspitalian seasoning

½ tsppaprika

1 tspsalt

½ tspblack pepper

12 ozpenne pasta

3 Tbspbutter

3cloves garlic

minced

1 ½ cupsheavy cream

or half-and-half

1 cupchicken broth

1 cupshredded mozzarella cheese

1 cupgrated parmesan cheese

Instructions

Step 1

Bring a large pot of salted water to a boil. Cook penne according to package directions. Drain and set aside.

Step 2

Heat 2 tbsp butter and olive oil in a large skillet over medium heat.

Step 3

Add chicken and season with garlic powder, Italian seasoning, paprika, salt, and pepper. Cook 6-8 minutes until browned and fully cooked. Remove and set aside.

Step 4

In the same skillet, melt 3 tbsp butter. Add minced garlic and cook 1 minute until fragrant.

Step 5

Pour in heavy cream and chicken broth. Stir and bring to a gentle simmer.

Step 6

Add mozzarella and Parmesan cheese. Stir until melted and smooth.

Step 7

Add cooked penne and toss until fully coated. Return chicken to skillet and mix gently.

Step 8

Garnish with parsley and extra Parmesan if desired. Serve warm.